Outcomes of Antenatal Booking Laboratory Investigations: A Report from Ilorin, Nigeria
Keywords:
laboratory, booking, care routine investigations, Antenatal testsAbstract
Background: Antenatal booking laboratory investigations provide information on the health status of antenatal women and at a glance highlight to the health provider areas to focus attention. The study aimed to describe the results of these investigations and emphasize their benefits.
Methods: A cross-sectionalstudy conducted at the University of Ilorin Teaching Hospital, Ilorin between January 2017 and December2018. Participants were antenatal women who had their booking laboratory investigations results reviewed at the antenatal clinic. The investigations included Packed Cell Volume, urinalysis, Veneral Disease Research Laboratory, blood group,
Rhesus typing, genotype, hepatitisB surface antigen, anti-hepatitis C antibody test and HIV screening. Data analysis was performed using SPSS version 21.0 and p<0.05 was significant.
Results: Among the 1,000antenatal women, the mean age was30.0±5 years while 420(42.0%) booked in the second trimester. The mean Packed Cell Volume at booking was 30±3%, 454(45.4%) had aneamia,260(26.0%) were diagnosed with HIV, 117(11.7%) had abnormal urinalysis results, Veneral Disease Research Laboratory test was reactive in 45(4.5%), 232(23.2%) were HBSAg reactive, 74(7.4%) were reactive to anti-HCV, 39 (3.9%) had genotype SS while 33(3.3%) were Rhesus D negative. There were associations between level of education (P=0.001), parity (P=0.001), or being married (P=0.003) and positive HIV result; being married (P=0.008) and reactive hepatitis B surface antigen test or level of education (P=0.002) and reactive Anti-HCV result.
Conclusion: Uptake of antenatal laboratory booking investigations should be encouraged to enhance detection and management of abnormalities thereby improving pregnancy outcome.
Downloads
References
1. Olamijulo AJ, Oluwole AA, Babah OA, Aderolu MB. Acceptance of focused antenatal care by pregnant Nigerian women and factors influencing it. Trop J ObstetGynaecol. 2015;32(2):90-6.
2. Ugalahi LO, Yusuf OB, Akinyemi JO, Adebowale AS. Regional differences in the optimal utilization of antenatal care in Nigeria. Sci J Public Health. 2016;4(1):43-8.
3. Bassi AP, Idoko L, Dibigbo-Ibeaji NM, Adeniyi OG, Ramyil MC, Ogundeko TO, et al. Prevalence of anaemia in pregnancy among women visiting antenatal clinic in Bingham University Teaching Hospital Jos, Nigeria. J Clin Med Research. 2016;5(3): 52-62.
4. Adeyemi A S, Bello-Ajao HT. Prevalence of Rhesus D negative blood type and the challenges of Rhesus D immunoprophylaxis among obstetric population in Ogbomoso, South western Nigeria. Ann Trop Med Public Health. 2016; 9:12-5.
5. Moses DL, Umanka YP, Ogbonnaya UN, Naancin IV, James GD. Distribution of haemoglobin genotype, ABO and Rhesus (D) blood groups among pregnant women in North Central Nigeria. World J Pharm Med Res. 2018;4(6):54-8.
6. Acheampong DO, Afoakwah MK, Boye A, Opoku R, Kwakye-Nuako G, Adokoh CK, et al. Evaluation of diagnostic methods and antimicrobial
susceptibility pattern of asymptomatic bacteriuria among pregnant women in Ashanti region, Ghana. J Explor Res Pharmacol. 2018;3(3):78-84.
7. Valentina Y, Sriranggaraj S. Pregnancy associated urinary tract infection: Prevalence and screening. Int J Curr Microbiol App Sci. 2016;5(1):452-60.
8. Eviatar N, Irit A, Eran H, Iftach S, Dafna Y, Shachaf S. Pregnancy outcome following bacteriuria in pregnancy and the significance of nitrites in urinalysis-a retrospective cohort study. J Perinatal Med. 2019;47(6):611-8.
9. Omo-Emmanuel UK, Ochei KC, Osuala EO, Obeagu E I, Onwuasoanya UF. Impact of prevention of mother to child transmission (PMTCT) of HIV on positivity rate in Kafanchan, Nigeria. Int J Curr Res Med Sci. 2017;3(2):28-34.
10. Koo K, Makin JD, Forsyth BW. Barriers to male-partner participation in programs to prevent mother-to- child HIV transmission in South Africa. AIDS Educ Prev. 2013; 25(1):14-24.
11. Pac WF, Revell PA, Eppes C. Syphilis during pregnancy: a preventable threat to maternal-fetal health. Am J Obstet Gynaecol. 2017;216(4):352-63.
12. Ede FR, Sheyin Z, Essien UC, Bigwan EI, Obiwelozor E E. Seroprevalence of syphilis in pregnant women attending Plateau specialist hospital, Jos, Nigeria. World J Pharm Res. 2017;6(4):1713-8.
13. Adhikare EH, Frame IJ, Hill E,Fatabhoy R, Strickland AL, Cavuoti D, et al. Abbott architect syphilis TP chemiluminescent immuno assay accurately diagnoses past or current syphilis in pregnancy. Am J Perinat. 2020;37(1):112-8.
14. Araoye MO. Research Methodology with Statistics for Health and Social sciences. Ilorin: Nathadex Press, 2003.
15. van'tHoog AH, Sarr A, Koster W, Delorme L, Diallo S, Sakande J, et al. A study to better understand under-utilization of laboratory tests for antenatal care in Senegal. PLoS ONE 2020;15(1): e0225710. Doi: https://doi.org/10.1371/journal.pone. 0225710
16. Oluwafemi FS, Fasoro AA, Akingbade AM, Faeji CO, Oni IO, Aboola AA, et al. Prevalence of anaemia among pregnant women registered at antenatal clinic of Ondo Specialist hospital, Ondo State, Nigeria. Asian Heam Res J. 2019;2(1):1-7.
17. Olatunbosun OA, Abasiattai AM, Bassey EA, James RS, Ibanga G, Morgan A. Prevalence of anaemia among pregnant women at
booking in University of Uyo Teaching Hospital, Uyo, Nigeria. Biomed Res Int 2014. Article ID 849080. DOI: http://dx.doi.org/10.1155/2014/849080.
18. Babatunde AS, Olawumi HO, Durotoye IA, Shittu AO, Adesina KT, Sani MA. Prevalence of anaemia among pregnant women at antenatal care booking in Ilorin, North Central Nigeria. Trop J Health Sci. 2017; 24(4):48-53.
19. S,Adeniran A Fawole AA, Fakeye OO, Ijaiya MA, Adesina KT. Grandmultiparity: Evaluating Obstetric and neonatal outcomes after eliminating confounders. Niger Postgrad Medical .2014;21(1):34-39.
20. Okonko IO, Osadebe AU, Onianwa O, Okereke S. Prevalence of HIV in a cohort of pregnant women attending a tertiary hospital in
Ibadan, Nigeria. J ImmunolInfec Diseases. 2019;7(1):7-12.
21. Jeremiah ZA. An assessment of the clinical utility of routine antenatal screening of pregnant women at first clinic attendance for haemoglobin genotypes, haematocrit, ABO and Rh blood groups in Port Harcourt, Nigeria. Afr J Reprod Health2005;9(3): 112-7.
22. Okafor II, Odugu BU, Ndibuagu EO. Patterns of routine antenatal laboratory test results at booking in Enugu State University Teaching Hospital, Enugu, Southeast Nigeria. IOSRJ Pharmacy 2017;7(5):41-48.
23. Nwabuko OC, Okoh DA, Iyalla D, Omunakwe H. Prevalence of sickle cell disease among pregnant women in a tertiary health center
in South-south Nigeria. Sub-Saharan Afr J Med 2016;3:132-6.
24. Adeniran AS, Kadri ER, Balogun OR. Pregnancy outcome in booked Nigerian Sickle cell patients. Nig Res J Clinical Sci 2012;2(2):93-100.
25. Nwosu BO, Eleje GU, Obi-Nwosu AL, Ahiarakwen IF, Akujobi CN, Egwuatu CC, et al. Is routine antenatal veneral disease research
laboratory test sill justified? Nigerian experience. Int J Women's Health 2015;7:41-46.
26. Awoyesuku PA, MacPepple DA, Kwosah NJ. Prevalence of seropositive VDRL cases amongst pregnant women at the Rivers State Teaching Hospital, Nigeria: Is routine screening for syphilis using VDRL still relevant? J Adv Med Res. 2019;1(2):1-7.
27. Jibrin YB, Kolo PM, Mohammed A, Sanya EO, Aliyu LD. Burden of hepatitis B and C infection on pregnant women in Bauchi, North-eastern Nigeria. Sub- Saharan Afr J Med. 2016;3:118-123.
28. Hassani P, TaheriEzbarami Z, ZagheriTafreshi M, AlaviMajd H. A Qualitative Study on Marital Challenges of Chronic Hepatitis B Patients, Iran Red Crescent Med J. 2017; 19(8): e55577. doi: 10.5812/ircmj.55577.
29. WHO. Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection. Geneva; WHO Press, 2015. Available at: https://www.who.int/hiv/pub/hepatitis/hepatitis-b-guidelines
30. Eassa S, Eissa M, Sharaf SM, Ibrahim MH, Hassane in OMA. Prevalence of hepatitis C infectionand evaluation of a health education program in El-Ghar village in Zagazig, Egypt. J Egypt Public Health Assoc. 2007;82(5&6):379-404.
Downloads
Published
Issue
Section
License
All articles published in the journal are licensed under a Creative Commons Attribution (CC BY) license(i.e CC Attribution-NonCommercial-ShareAlike 4.0), allowing others to share, distribute, and build upon the work, provided the original author(s) and source are properly cited. Authors retain the copyright of their work.
